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Unique identifier: 526381c5-d8f1-4519-8627-af96a385fea4

1. Descrição do cargo/posição/bolsa
1. Job description

Job:
PhD Scientific Researcher Recruitment

Job/Fellowship Reference: # 2678; FCiências.ID/2018/DL57/BioISI/14; Project iDrugCF

Main research field: Biological sciences

Sub research field:

Job summary:

I - Admission Requirements Portuguese nationals, foreign and stateless persons may submit applications to this selection procedure, provided they hold a doctoral degree1 in Biology, Biochemistry, Biomedicine or akin areas, with preference with specialised skills and/or expertise in molecular and cell biology of membrane proteins, and preference will be given to candidates who comply with the following requirements: a) Researchers with a PhD granted less than 5 years will be preferred. b) Demonstrated scientific and/or professional experience in fluorescence microscopy, image analysis, genome editing, high-throughput approaches to drug discovery and/ or electrophysiology.

Job description:

# 2678 Public Notice - International Selection Procedure PhD Scientific Researcher Recruitment FCiências.ID/2018/DL57/BioISI/14 FCiências.ID - Associação para a Investigação e Desenvolvimento de Ciências, through its Chairman of the Board of Directors, hereby announces the opening of an international call for the recruitment of a scientific researcher with a PhD degree, within the scope of project "iDrugCF-Identification of New Drugs for Cystic Fibrosis" (ref. PTDC/MED-QUI/28800/2017), in the form of an employment contract with an uncertain term, according to the Portuguese Labour Code and Decree-Law No. 57/2016, of August 29th, as amended by Law No. 57/2017, of July 19th, and complementary legislation. I - Admission Requirements Portuguese nationals, foreign and stateless persons may submit applications to this selection procedure, provided they hold a doctoral degree1 in Biology, Biochemistry, Biomedicine or akin areas, with preference with specialised skills and/or expertise in molecular and cell biology of membrane proteins, and preference will be given to candidates who comply with the following requirements: a) Researchers with a PhD granted less than 5 years will be preferred. b) Demonstrated scientific and/or professional experience in fluorescence microscopy, image analysis, genome editing, high-throughput approaches to drug discovery and/ or electrophysiology. 1 Applicants with doctoral degrees obtained in foreign countries need, in accordance with Decree-Law No. 341/2007, of October 12th, as regulated by Government Order No. 227/2017, of July 25th, to be recognized as holders of a doctoral degree, with all inherent entitlements. Applicants to whom, under the terms of Decree-Law No. 283/83, of June 21th, equivalence or recognition of the degree of Doctor has been granted are valid. Proof of equivalence, recognition and registration of the doctoral degree should be made for contract signature. II. Applicable Law 1. Decree-Law No. 57/2016, of August 29th, in the wording conferred on it by Law No. 57/2017, of July 19th (RJEC), taking also into account the provisions of Regulatory Decree No. 11-A/2017, of December 29th; 2. Portuguese Labour Code, as approved by Law No. 7/2009, of February 12th, in its current version (CT); 3. Administrative Procedure Code, as published in Decree-Law No. 4/2015, of January 7th, in its current version (CPA). III. Work Plan The objective of the work plan is to identify new small molecules which, either on their own or in combination with existing CFTR modulators, improve the lives of CF patients with the F508del mutation or other rare (orphan) mutations sharing the same molecular defect but no treatment. The work will focus on: 1) screening of a library of small molecules by high-throughput (HT) microscopy screens by the assessment of rescue to the plasma membrane of CFTR mutants and determine their mechanism of action (MoA); 2) to pre-clinically validate the efficacy for top lead compounds in primary tissues from Cystic Fibrosis patients (intestinal organoids and nasal cells). The plan of work in included in tasks 1 (1.2), 3 (3.1; 3.2) e 4 (4.1, 4.2) of the project. IV. Composition of the Jury In accordance to article 13 of the RJEC, the members of the jury are: • President – Professor Margarida Duarte Amaral, FCUL • 1st Evaluator – Prof Carlos Farinha, FCUL • 2nd Evaluator – Prof Rui Malhó, FCUL • 1st Alternate Evaluator – Prof. Margarida Gama-Carvalho, FCUL • 2nd Alternate Evaluator – Prof. Margarida Telhada, FCUL V. Place of work Work will be developed at the facilities of BioISI: Biosystems and Integrative Sciences Institute, Campo Grande, Lisboa, Portugal. VI. Contract Duration The full-time employment contract with an uncertain term is expected to start on February 1st, and will last until the Work Plan referred to in section III is completed. It will have an expected duration of 15 months, with a maximum duration of 6 years, including an initial experimental trial period of 30 days. VII. Monthly Allowance The gross monthly salary entitle is stipulated in clause 1 of article 5 of the Regulatory Decree No. 11-A/2017, of December 29th, corresponding to level 33 of the Consolidated Table of Allowances, as approved by Government Order No. 1553-C/2008, of December 31st, being 2,128.34 Euros, plus holiday and Christmas allowances, as well as food allowance, in value and conditions for workers with a legal relationship of employment under the Labour Code. VIII. Evaluation of applications 1. Failure to comply with the Admission Requirements implies the non-admission of candidates in absolute merit. 2. According to article 5 of the RJEC, the selection of the candidates approved in absolute merit will rely on the evaluation of their scientific and curricular achievements in the last five years, taking into consideration the quality and relevance of the scientific production, and the professional activity indicated as more relevant by the candidate for the project. 3. The final classification of candidates is given on a scale of 0 to 100%. 4. Evaluation of the relative merit of candidates, will rely on the following criteria: a) Participation in relevant scientific projects in the above areas – 20 %; b) Scientific publications in the above areas - 65 %; c) Assessment of the references provided by the candidate - 5 %; d) Interview, if deemed necessary by the jury - 10% 5. The jury may decide to interview the best ranked candidates [in criteria a) to d) of paragraph 4)] for clarifications and improved explanations of curricular elements. 6. The jury will deliberate by means of a roll-call vote based on the evaluation criteria. 7. Minutes of the jury meetings will be drawn up, summarizing all relevant elements considered by jury members, as well as their individual votes and justifications. 8. After completion of the evaluation process, the jury will draw up a ranking of successful candidates with their classifications. 9. Hiring will be decided by the Chairman of the Board of Directors of FCiências.ID, based on the final jury recommendation. 10. The evaluation results will be published on the website of the FCiências.ID ("Concursos" tab). The candidates will be individually notified of the evaluation results by e-mail sent to the address indicated in the "Personal Data" section of the submitted form. 11. With the notification referred to in paragraph 10, the hearing phase of interested parties referred to in Article 121 et seq. of the CPA will begin, and last for ten working days. 12. The possible pronouncement of the candidate in a prior hearing must be addressed to the President of the jury and submitted in writing to fciencias.id@fciencias-id.pt. The President of the jury will convene a jury’s meeting to produce the final decision, within thirty working days. 13. Within five working days of the final jury decision, the Board of Directors Chairman of FCiências.ID will approve it and the candidates will be notified. 14. The communication between FCiências.ID and the candidates will be electronic and will comply with the following rules: a) At the time of electronic submission of any document - namely in the case of paragraph no 11 - the candidates must generate proof of "sent message". b) FCiências.ID will send an email message acknowledging documents received to the email address used by the candidates, within two working days. c) In case of absence of a confirmation receipt by FCiências.ID – showing the possibility of technical problems that should neither be the responsibility of the candidate nor FCiências.ID - the candidates should contact FCiências.ID, with the proof referred to in point (a), to ensure delivery and proper receipt of the documents concerned. IX. Compliance with public policies 1. FCiências.ID actively promotes a policy of non-discrimination and equal access, so that no candidate can be privileged, benefited, disadvantaged or deprived of any right or exempt from any duty due to, inter alia, ancestry, age, sex, sexual orientation, marital status, family status, economic situation, education, social origin or condition, genetic heritage, reduced working capacity, disability, chronic illness, nationality, ethnic origin or race, territory of origin, language, religion, political or ideological beliefs and trade union membership. 2. Under the terms of D.L. No. 29/2001, of February 3, a disabled candidate has a preference in equal classification, which prevails over any other legal preference. Candidates must declare their respective degree of disability, the type of disability and the means of communication / expression to be used in the selection process, under the terms of the above-mentioned diploma. X. Submission of Applications 1. The present call will be open from 14 December 2018 until 15 January 2019. 2. The application and all the required documents may be submitted in Portuguese or English. 3. Applications will be submitted online, through the electronic platform of FCiências.ID (http://concursos.fciencias-id.pt). 4. On the electronic platform, applicants will complete a mandatory section on Personal Data [name, address, date of birth, contact email, nationality and scientific identifiers] and upload files with the documents listed below: i. Detailed curriculum vitae - mandatory; ii. A motivation letter clearly demonstrating that the candidate has an adequate profile for the position and fully complies with the Admission Requirements - mandatory; iii. Up to five publications relevant for the objectives of the Work Plan - mandatory; iv. Digital copies of documents proving formal academic degrees (PhD) and/or other scientific and professional qualifications - original documents must be provided in case of actual recruitment- mandatory; v. Other documents that candidates consider relevant for the assessment of their scientific merit, or to declare the personal situation in the cases covered in section IX-2 of this Notice - optional. 5. By decision of the Chairman of the Board of Directors of FCiências.ID, candidates who do not submit the documents identified in paragraph 4 will not be admitted to the call. In case of doubts, the Chairman may also invite candidates to substantiate specific data or statements with official supporting documents, before accepting the candidates’ submission. This Public Note was approved by the jury on 11 December 2018


Vacant posts: 1

Type of contract: Temporary

Job country: Portugal

Job city: Lisboa

Job company/institute: Unidade de Investigação BioISI: Biosystems and Integrative Sciences Institute, Campo Grande, Lisboa, Portugal.


Application deadline: 15 Janeiro 2019
(The Application's deadline must be confirmed on the Job Description)

2. Dados de contactos da organização
2. Organization contact data

Organization/institute: FCiências.ID – Associação para a Investigação e Desenvolvimento de Ciências

Address:
Bloco C1 - 3.º Piso, Campo Grande
Lisboa - 1749-016
Portugal

Email: concursos@fciencias-id.pt

Website: not available

3. Habilitações académicas
3. Required education Level


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4. Línguas exigidas
4. Required languages


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5. Experiência exigida em investigação
5. Required research experience


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